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  • MROZEK Ségolène      Prendre rendez-vous en ligne

    • Consultations
    • Diplômes
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    Du lundi au vendredi, selon l'organisation : 08h30-12h  et 14h-18h
    Thèse de sciences. 04 décembre 2017. Université Paul Sabatier, Toulouse III. Signature biologique de l’agression cérébrale traumatique et hypoxique. 
    Docteur en Médecine, Spécialité Anesthésie-Réanimation, Université d’Auvergne, Octobre 2011. Thèse d’exercice : Impact des biomarqueurs de l’inflammation dans la définition du SDRA. 
    Master 2 Recherche domaine « physiologie de l’exercice, science du mouvement humain », Montpellier. Dysfonction Diaphragmatique Induite par la Ventilation: mise au point d’un modèle murin et rôle du récepteur à la Ryanodine 1. Juin 2010. Rang 1. 
    Diplôme Inter-Universitaire : Echocardiographie doppler (interrégion sud-est), Juin 2010. 
    Diplôme Inter-Universitaire : Insuffisance circulatoire aigue (Pr J.L Teboul), Juin 2008. 
    Master 1 domaine « sciences de la vie et de la santé »: « douleur et sciences du comportement » et « physiologie et physiopathologie de la neuromédiation », Juin 2007.
    - Anesthésiste-réanimateur, Clinique Pasteur, Toulouse, oct. 2020 - maintenant
    - Cheffe d’Unité d’anesthésie-réanimation neurochirurgicale, CHU Purpan, PPR, Toulouse. décembre 2018 – mai 2020
    - Praticien hospitalier temps plein titulaire, sept. 2015 - juin 2020
    Pôle Anesthésie-réanimation, CHU Toulouse, Neurochirurgie, Hôpital PPR
    - Chef de clinique des universités-assistants des hôpitaux, mai 2012 – sept. 2014
    Pôle Anesthésie-réanimation, CHU Toulouse, Neurochirurgie, Hôpital Rangueil et PPR
    • 1. Acetaminophene-induced hypotension in intensive care unit: A prospective study. Mrozek S., Constantin J.M, Futier E., Zenut M., Ghardes G., Cayot-Constantin S., Bonnard M., Ait-Bensaid N., Eschalier A., Bazin J.E. Ann Fr Anesth Reanim, 2009.
      2. Soluble form of the receptor for advanced glycation end products is a marker of acute lung injury but not of severe sepsis in critically ill patients. Jabaudon M, Futier E, Roszyk L, Chalus E, Guerin R, Petit A, Mrozek S, Perbet S, Cayot-Constantin S, Chartier C, Bazin JE, Constantin JM. Crit Care Med. 2011
      3. Rapid onset of specific diaphragm weakness in a healthy murine model of ventilator-induced diaphragmatic dysfunction. Mrozek S, Jung B, Petrof BJ, Pauly M, Roberge S, Lacampagne A, Cassan C, Thireau J, Molinari N, Futier E, Scheuermann V, Constantin JM, Matecki S, Jaber. Anesthesiology 2012
      4. Brain temperature: physiology and pathophysiology after brain injury. Mrozek S, Vardon F, Geeraerts T. Anesthesiol Res Pract. 2012
      5. The management of femur shaft fracture associated with severe traumatic brain injury.  Mrozek S, Gaussiat F, Geeraerts T. Ann Fr Anesth Reanim. 2013
      6. How can we determine the best cerebral perfusion pressure in pediatric traumatic brain injury? Vuillaume C, Mrozek S, Fourcade O, Geeraerts T. Ann Fr Anesth Reanim 2013. 
      7. Brain ischemia with normal cerebral perfusion pressure after TBI: a place for increasing arterial carbon dioxide pressure? Lonjaret L, Mrozek S, Fourcade O, Geeraerts T. Minerva Anestesiol. 2014.
      8. Brain empyena due to Ochrobactrum anthropi. Mrozek S, Dupuy M, Hoarau L, Lourtet J, Martin-Blondel G, Geeraerts T. Med Mal Infect. 2014.
      9. Biomarkers and acute brain injuries: Interest and limits. Mrozek S., Dumurgier J., Citerio G., Mebazaa A., Geeraerts T. Critical Care 2014. 
      10. Assessment of brain midline shift using sonography in neurosurgical ICU patients. Motuel J, Biette I, Srairi M, Mrozek S, Kurrek MM, ChaynesP, Cognard C, Fourcade O, Geeraerts T. Critical Care 2014
      11. The optimal time between clinical brain death diagnosis and confirmation using CT angiography : a retrospective study. Kerhuel L, Srairi M, Georget G, Bonneville F, Mrozek S, Mayeur N, Lonjaret L, Sacrista S, Hermant N, Marhar F, Gaussiat F, Abaziou T, Osinski D, Le Gaillard B, Menut R, Larcher C, Fourcade O, Geeraerts T.Minerva Anestesiol. 2016 Sep 13. 
      12. Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation. Matecki S, Dridi H, Jung B, Saint N, Reiken SR, Scheuermann V, Mrozek S, Santulli G, Umanskaya A, Petrof BJ, Jaber S, Marks AR, Lacampagne A. Proc Natl Acad Sci U S A. 2016 Aug 9. 
      13. Successful treatment of inverted Takotsubo cardiomyopathy after severe traumatic brain injury with milrinone after dobutamine failure. Mrozek S, Srairi M, Marhar F, Delmas C, Gaussiat F, Abaziou T, Larcher C, Atthar V, Menut R, Fourcade O, Geeraerts T. Heart Lung. 2016 Sep-Oct. 
      14. Cerebral and extracerebral vulnerability to hypoxic insults after diffuse traumatic brain injury in rats. Mrozek S, Luzi A, Gonzalez L, Kerhuel L, Fourcade O, Geeraerts T. Brain Res. 2016 Sep. 
      15. Accidental hypothermia in severe trauma. Vardon F, Mrozek S, Geeraerts T, Fourcade O. Anaesth Crit Care Pain Med. 2016 May 13. 
      16. Elevated Plasma Levels of sRAGE are Associated with Non-Focal CT-Based Lung Imaging in ARDS patients.: A Prospective Multicenter Study. Mrozek S, Jabaudon M, Jaber S, Paugam-Burtz C, Lefrant JY, Rouby JJ, Asehnoune K, Allaouchiche B, Baldesi O, Leone M, Lu Q, Bazin JE, Roszyk L, Sapin V, Futier E, Pereira B, Constantin JM; Azurea network. Chest. 2016 Mar 23. 
      17. Brain-lung crosstalk: Implications for neurocritical care patients. Mrozek S, Constantin JM, Geeraerts T. World J Crit Care Med. 2015 Aug 4.
      18. A negative pressure wound therapy for complex infected cranial defects overlying dura mater: An effective and safe procedure. Dupuy M, Da Silva M, Mrozek S, Sol JC, de Bonnecaze G, Chaput B. J Plast Reconstr Aesthet Surg. 2017 Sep. 
      19. A multi-faceted strategy to reduce ventilation-associated mortality in brain-injured patients. The BI-VILI project: a nationwide quality improvement project. Asehnoune K, Mrozek S, Perrigault PF, Seguin P, Dahyot-Fizelier C, Lasocki S, Pujol A, Martin M, Chabanne R, Muller L, Hanouz JL, Hammad E, Rozec B, Kerforne T, Ichai C, Cinotti R, Geeraerts T, Elaroussi D, Pelosi P, Jaber S, Dalichampt M, Feuillet F, Sebille V, Roquilly A; BI-VILI study group. Intensive Care Med. 2017 Jul.
      20. Reversible Cerebral Vasoconstriction Syndrome with Intracranial Hypertension: Should Decompressive Craniectomy Be Considered? Mrozek S, Lonjaret L, Jaffre A, Januel AC, Raposo N, Boetto S, Albucher JF, Fourcade O, Geeraerts T. Case Rep Neurol. 2017 Jan 24.
      21. Letter: Hypnosis for Awake Surgery of Low-Grade Gliomas: Description of the Method and Psychological Assessment. Srairi M, Mrozek S, Roux F, Geeraerts T. Neurosurgery. 2017 Feb 1.
      22. French intensive care unit organisation. Leone M, Constantin JM, Dahyot-Fizelier C, Duracher-Gout C, Joannes-Boyau O, Langeron O, Legrand M, Mahjoub Y, Mirek S, Mrozek S, Muller L, Orban JC, Quesnel C, Roquilly A, Virat A, Capdevila X. Anaesth Crit Care Pain Med. 2018 Dec;
      23. "Real life" impact of anesthesia strategy for mechanical thrombectomy on the delay, recanalization and outcome in acute ischemic stroke patients.Vukasinovic I, Darcourt J, Guenego A, Michelozzi C, Januel AC, Bonneville F, Tall P, Mrozek S, Geeraerts T, Olivot JM.J Neuroradiol. 2018 Oct 30.
      24. Transient diabetes insipidus after severe subarachnoid hemorrhage: not always central. Abaziou T, Mrozek S, Srairi M, Gaussiat F, Marhar F, Osinski D, Menut R, Larcher C, Atthar V, Brauge D, Sol JC, Fourcade O, Geeraerts T. J Neurosurg Sci. 2018 Oct 
      25. Plasma sRAGE is independently associated with increased mortality in ARDS: a meta-analysis of individual patient data.
      Jabaudon M, Blondonnet R, Pereira B, Cartin-Ceba R, Lichtenstern C, Mauri T, Determann RM, Drabek T, Hubmayr RD, Gajic O, Uhle F, Coppadoro A, Pesenti A, Schultz MJ, Ranieri MV, Brodska H, Mrozek S, Sapin V, Matthay MA, Constantin JM, Calfee CS. Intensive Care Med. 2018 Sep
      26. Multicenter study of 37 pediatric patients with SCIWORA or other spinal cord injury without associated bone lesion. Brauge D, Plas B, Vinchon M, Charni S, Di Rocco F, Sacko O, Mrozek S, Sales de Gauzy J. Orthop Traumatol Surg Res. 2020 Feb. 
      27. Sedation versus general anaesthesia in endovascular therapy for anterior circulation acute ischaemic stroke: the multicentre randomised controlled AMETIS trial study protocol. Chabanne R, Fernandez-Canal C, Degos V, Lukaszewicz AC, Velly L, Mrozek S, Perrigault PF, Molliex S, Tavernier B, Dahyot-Fizelier C, Verdonk F, Caumon E, Masgrau A, Begard M, Chabert E, Ferrier A, Jaber S, Bazin JE, Pereira B, Futier E; ANARLF Network and the AMETIS study group. BMJ Open. 2019 Sep 13 
      28. Consider brain perfusion imaging rather than just the delay from symptoms onset to indicate reperfusion strategies after stroke: Implications for perioperative care. Geeraerts T, Mrozek S, Monet C, Olivot JM. Anaesth Crit Care Pain Med. 2019 Aug 
      29. What Is the Impact of Physical Effort on the Diagnosis of Concussion? Dechambre X, Carling C, Mrozek S, Pillard F, Decq P, Piscione J, Yrondi A, Brauge D. Clin J Sport Med. 2019 Jun 14. 
      30. Cerebral Expression of Glial Fibrillary Acidic Protein, Ubiquitin Carboxy-Terminal Hydrolase-L1, and Matrix Metalloproteinase 9 After Traumatic Brain Injury and Secondary Brain Insults in Rats. Mrozek S, Delamarre L, Capilla F, Al-Saati T, Fourcade O, Constantin JM, Geeraerts T. Biomark Insights. 2019 Jun 4
      31. Pharmacotherapy of sodium disorders in neurocritical care. Mrozek S, Rousset D, Geeraerts T. Curr Opin Crit Care. 2019 Apr
      32. "Real life" impact of anesthesia strategy for mechanical thrombectomy on the delay, recanalization and outcome in acute ischemic stroke patients. Vukasinovic I, Darcourt J, Guenego A, Michelozzi C, Januel AC, Bonneville F, Tall P, Mrozek S, Geeraerts T, Olivot JM, Cognard C; Toulouse Stroke Group. J Neuroradiol. 2019 Jul
      33. Can prone positioning be a safe procedure in patients with acute brain injury and moderate-to-severe acute respiratory distress syndrome? Bernon P, Mrozek S, Dupont G, Dailler F, Lukaszewicz AC, Balança B. Crit Care 2021
      34. Diagnostic accuracy of a revised computed tomography angiography score for brain death confirmation, combining supra-tentorial arteries and infra-tentorial veins. Srairi M, Meluchova Z, Paoletti M, Ahmad M, Abaziou T, Atthar V, Georget G, Mrozek S, Larcher C, Osinski D, Menut R, Gaussiat F, Marhar F, Riu B, Silva S, Seguin T, Bounes FV, Georges B, Sol JC, Brauge D, Minville V, Fourcade O, Bonneville F, Geeraerts T.Eur J Radiol. 2020 
      35. Cerebral Venous Thrombosis and Subdural Collection in a Comatose Patient: Do Not Forget Intracranial Hypotension. A Case Report. Paris D, Rousset D, Bonneville F, Fabre N, Faguer S, Huguet-Rigal F, Larcher C, Martin C, Osinski D, Gaussiat F, Delamarre L, Brauge D, Fourcade O, Geeraerts T, Mrozek S. Headache. 2020 
      36. How to resume elective surgery in light of COVID-19 post-pandemic propofol shortage: The common concern of anaesthesists and surgeons. Charbonneau H, Mrozek S, Pradere B, Cornu JN, Misrai V.Anaesth Crit Care Pain Med. 2020 
      37. Incidence and predicting factors of perioperative complications during monitored anesthesia care for awake craniotomy.
      Abaziou T, Tincres F, Mrozek S, Brauge D, Marhar F, Delamarre L, Menut R, Larcher C, Osinski D, Cinotti R, Sol JC, Fourcade O, Roux FE, Geeraerts T.J Clin Anesth. 2020
      38 Choice of fluid for critically ill patients: An overview of specific situations.
      Joannes-Boyau O, Roquilly A, Constantin JM, Duracher-Gout C, Dahyot-Fizelier C, Langeron O, Legrand M, Mirek S, Mongardon N, Mrozek S, Muller L, Orban JC, Virat A, Leone M; Critical Care Committee of the French Society of Anaesthesia and Intensive Care (SFAR).Anaesth Crit Care Pain Med. 2020
      39. COVID-19-associated acute necrotising encephalopathy successfully treated with steroids and polyvalent immunoglobulin with unusual IgG targeting the cerebral fibre network.
      Delamarre L, Gollion C, Grouteau G, Rousset D, Jimena G, Roustan J, Gaussiat F, Aldigé E, Gaffard C, Duplantier J, Martin C, Fourcade O, Bost C, Fortenfant F, Delobel P, Martin-Blondel G, Pariente J, Bonneville F, Geeraerts T; NeuroICU Research Group.J Neurol Neurosurg Psychiatry. 2020
      40. Crosstalk between brain, lung and heart in critical care. Mrozek S, Gobin J, Constantin JM, Fourcade O, Geeraerts T.Anaesth Crit Care Pain Med. 2020